Decade after menopause poses highest risk of Alzheimer's for women with ApoE4 gene

Recent research has challenged previously accepted notions that the gene variant ApoE4 gave its female carriers a greater risk of developing Alzheimer’s than men. older woman thinking in a park

A team of researchers led by Dr. Scott Neu of the University of Southern California and supported in part by NIA found that gender differences in Alzheimer’s risk are not as clear as once thought, and that the decade or so after menopause poses the most significant risk for women. The scientists examined clinical and genetic data from nearly 58,000 study participants to provide a more detailed, nuanced picture of sex difference and the gene variant.