A number of researchers think that it’s time to re-consider the idea of infection as a root cause of Alzheimer's disease. These scientists point to studies that reveal the presence of a microbe that is eventually activated by a stressor, thus causing inflammation which could possibly trigger the disease. Even though there have been many studies supporting their theory over the years, these scientists don't feel that they are being heard. An editorial in the Journal of Alzheimer’s Disease compares this lack of acceptance of an alternative to the most popular theory to historic controversies related to other diseases.